Publications – University of Copenhagen

Flowcytometry > Publications

Publications

On this page, you can find a number of publications where CFFC equipment or knowhow has been used. Please note that this is not a complete list of publications.

If you have used a CFFC instruments to obtain results which will be published in a paper you write, please make sure to acknowledge CFFC.
In addition, we would be grateful to receive information when a paper, in which CFFC has been acknowledged, is published. Thereby, your paper will also be published on our website.

How to acknowledge CFFC:
"Core Facility for Flow Cytometry, Faculty of Health and Medical Sciences, University of Copenhagen".

2017

Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus.

Buus TB, Ødum N, Geisler C, Lauritsen JPH.

Nat Commun. 2017 Dec 4;8(1):1911. doi: 10.1038/s41467-017-01963-w.

2016

Development of interleukin-17-producing Vγ2+ γδ T cells is reduced by ICOS signaling in the thymus.

Buus TB, Schmidt JD, Bonefeld CM, Geisler C, Lauritsen JP.

Oncotarget. 2016 Apr 12;7(15):19341-54. doi: 10.18632/oncotarget.8464.

PB1 as a potential target for increasing the breadth of T-cell mediated immunity to Influenza A.

Uddbäck IE, Steffensen MA, Pedersen SR, Nazerai L, Thomsen AR, Christensen JP.

Sci Rep. 2016 Oct 7;6:35033. doi: 10.1038/srep35033.

Early life vaccination: Generation of adult-quality memory CD8+ T cells in infant mice using non-replicating adenoviral vectors.

Nazerai L, Bassi MR, Uddback IE, Holst PJ, Christensen JP, Thomsen AR.Sci Rep. 2016 Dec 8;6:38666. doi: 10.1038/srep38666.

Vaccination with Replication Deficient Adenovectors Encoding YF-17D Antigens Induces Long-Lasting Protection from Severe Yellow Fever Virus Infection in Mice.

Bassi MR, Larsen MA, Kongsgaard M, Rasmussen M, Buus S, Stryhn A, Thomsen AR, Christensen JP.

PLoS Negl Trop Dis. 2016 Feb 17;10(2):e0004464. doi: 10.1371/journal.pntd.0004464. eCollection 2016 Feb.

Vaccine Targeting of Subdominant CD8+ T Cell Epitopes Increases the Breadth of the T Cell Response upon Viral Challenge, but May Impair Immediate Virus Control.

Steffensen MA, Pedersen LH, Jahn ML, Nielsen KN, Christensen JP, Thomsen AR.

J Immunol. 2016 Mar 15;196(6):2666-76. doi: 10.4049/jimmunol.1502018. Epub 2016 Feb 12.

Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virus.

Uddback IE, Pedersen LM, Pedersen SR, Steffensen MA, Holst PJ, Thomsen AR, Christensen JP.

Sci Rep. 2016 Feb 1;6:20137. doi: 10.1038/srep20137.

Immunogenicity of HLA Class I and II Double Restricted Influenza A-Derived Peptides.

Pedersen SR, Christensen JP, Buus S, Rasmussen M, Korsholm KS, Nielsen M, Claesson MH.

PLoS One. 2016 Jan 5;11(1):e0145629. doi: 10.1371/journal.pone.0145629. eCollection 2016.

2015

The major diversification of Vγ1.1+ and Vγ2+ thymocytes in mice occurs after commitment to the γδ T-cell lineage.

Buus TB, Geisler C, Lauritsen JP.

Eur J Immunol. 2016 Oct;46(10):2363-2375. doi: 10.1002/eji.201646407. Epub 2016 Aug 15.

CD8+ T cells complement antibodies in protecting against yellow fever virus.

Bassi MR, Kongsgaard M, Steffensen MA, Fenger C, Rasmussen M, Skjødt K, Finsen B, Stryhn A, Buus S, Christensen JP, Thomsen AR.

J Immunol. 2015 Feb 1;194(3):1141-53. doi: 10.4049/jimmunol.1402605. Epub 2014 Dec 24.

2014

CD8+ T Cells Complement Antibodies in Protecting against Yellow Fever Virus.

Bassi MR, Kongsgaard M, Steffensen MA, Fenger C, Rasmussen M, Skjødt K, Finsen B, Stryhn A, Buus S, Christensen JP, Thomsen AR.

J Immunol. 2015 Feb 1;194(3):1141-53. doi: 10.4049/jimmunol.1402605. Epub 2014 Dec 24.

Suppressors of cytokine signaling 1 and 3 are upregulated in brain resident cells in response to virus-induced inflammation of the central nervous system via at least two distinctive pathways.

Steffensen MA, Fenger C, Christensen JE, Jørgensen CK, Bassi MR, Christensen JP, Finsen B, Thomsen AR.

J Virol. 2014 Dec;88(24):14090-104. doi: 10.1128/JVI.01346-14. Epub 2014 Sep 24.

Co-expression of tumor antigen and interleukin-2 from an adenoviral vector augments the efficiency of therapeutic tumor vaccination.

Jensen BA, Steffensen MA, Nielsen KN, Christensen JP, Thomsen AR, Holst PJ.

Mol Ther. 2014 Dec;22(12):2107-17. doi: 10.1038/mt.2014.130. Epub 2014 Jul 15.

Priming of CD8 T cells by adenoviral vectors is critically dependent on B7 and dendritic cells but only partially dependent on CD28 ligation on CD8 T cells.

Nielsen KN, Steffensen MA, Christensen JP, Thomsen AR.

J Immunol. 2014 Aug 1;193(3):1223-32. doi: 10.4049/jimmunol.1400197. Epub 2014 Jun 20.

CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine/Chemokine Receptor Complex in Patients with AMD.

Falk MK, Singh A, Faber C, Nissen MH, Hviid T, Sørensen TL.

PLoS One. 2014 Dec 15;9(12):e112473. doi: 10.1371/journal.pone.0112473. eCollection 2014.

Early and exudative age-related macular degeneration is associated with increased plasma levels of soluble TNF receptor II.

Faber C, Jehs T, Juel HB, Singh A, Falk MK, Sørensen TL, Nissen MH.

Acta Ophthalmol. 2014 Nov 2. doi: 10.1111/aos.12581. [Epub ahead of print]

Inflammation-induced chemokine expression in uveal melanoma cell lines stimulates monocyte chemotaxis.

Jehs T, Faber C, Juel HB, Bronkhorst IH, Jager MJ, Nissen MH.

Invest Ophthalmol Vis Sci. 2014 Jul 29;55(8):5169-75. doi: 10.1167/iovs.14-14394.

Dysregulation of CXCR3 expression on peripheral blood leukocytes in patients with neovascular age-related macular degeneration.

Falk MK, Singh A, Faber C, Nissen MH, Hviid T, Sørensen TL.

Invest Ophthalmol Vis Sci. 2014 May 8;55(7):4050-6. doi: 10.1167/iovs.14-14107.

Blood expression levels of chemokine receptor CCR3 and chemokine CCL11 in age-related macular degeneration: a case-control study.

Falk MK, Singh A, Faber C, Nissen MH, Hviid T, Sørensen TL.

BMC Ophthalmol. 2014 Feb 27;14:22. doi: 10.1186/1471-2415-14-22.

2013
Qualitative and quantitative analysis of adenovirus type 5 vector-induced memory CD8 T cells: not as bad as their reputation.
Steffensen MA, Holst PJ, Steengaard SS, Jensen BA, Bartholdy C, Stryhn A, Christensen JP, Thomsen AR.
J Virol. 2013 Jun;87(11):6283-95. doi: 10.1128/JVI.00465-13. Epub 2013 Mar 27.
Age-Related Macular Degeneration Is Associated with Increased Proportion of CD56+ T Cells in Peripheral Blood.
Faber C, Singh A, Krüger Falk M, Juel HB, Sørensen TL, Nissen MH.
Ophthalmology. 2013 Jun 6. doi:pii: S0161-6420(13)00361-8. 10.1016/j.ophtha.2013.04.014. [Epub ahead of print]
Inflammatory cytokines protect retinal pigment epithelial cells from oxidative stress-induced death.
Juel HB, Faber C, Svendsen SG, Vallejo AN, Nissen MH.
PLoS One. 2013 May 21;8(5):e64619. doi: 10.1371/journal.pone.0064619.
The expression and functional activity of membrane-bound human leukocyte antigen-G1 are influenced by the 3'-untranslated region.
Svendsen SG, Hantash BM, Zhao L, Faber C, Bzorek M, Nissen MH, Hviid TV.
Hum Immunol. 2013 Jul;74(7):818-27. doi: 10.1016/j.humimm.2013.03.003. Epub 2013 Apr 10.
CD4(+) T cells producing interleukin (IL)-17, IL-22 and interferon-γ are major effector T cells in nickel allergy.
Dyring-Andersen B, Skov L, Løvendorf MB, Bzorek M, Søndergaard K, Lauritsen JP, Dabelsteen S, Geisler C, Bonefeld CM.Contact Dermatitis. 2013 Jun;68(6):339-47. doi: 10.1111/cod.12043.

PKC-θ exists in an oxidized inactive form in naive human T cells.

von Essen MR, Kongsbak M, Levring TB, Hansen AK, Boding L, Lauritsen JP, Woetmann A, Baier G, Ødum N, Bonefeld CM, Geisler C.

Eur J Immunol. 2013 Jun;43(6):1659-66. doi: 10.1002/eji.201243140. Epub 2013 Apr 12.

MHC Class II Tetramers Made from Isolated Recombinant α and β Chains Refolded with Affinity-Tagged Peptides.

Braendstrup P, Justesen S, Osterbye T, Nielsen LL, Mallone R, Vindeløv L, Stryhn A, Buus S.

PLoS One. 2013 Sep 2;8(9):e73648. doi: 10.1371/journal.pone.0073648.

Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity.

Lavrsen K, Madsen CB, Rasch MG, Woetmann A, Ødum N, Mandel U, Clausen H, Pedersen AE, Wandall HH.

Glycoconj J. 2013 Apr;30(3):227-36. doi: 10.1007/s10719-012-9437-7. Epub 2012 Aug 10.

TH17 cell induction and effects of IL-17A and IL-17F blockade in experimental colitis.

Wedebye Schmidt EG, Larsen HL, Kristensen NN, Poulsen SS, Lynge Pedersen AM, Claesson MH, Pedersen AE.

Inflamm Bowel Dis. 2013 Jul;19(8):1567-76. doi: 10.1097/MIB.0b013e318286fa1c.

 2012

A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin.
Egerod KL, Engelstoft MS, Grunddal KV, Nøhr MK, Secher A, Sakata I, Pedersen J, Windeløv JA, Füchtbauer EM, Olsen J, Sundler F, Christensen JP, Wierup N, Olsen JV, Holst JJ, Zigman JM, Poulsen SS, Schwartz TW.
Endocrinology. 2012 Dec;153(12):5782-95. doi: 10.1210/en.2012-1595. Epub 2012 Oct 12.

Increased immunogenicity and protective efficacy of influenza M2e fused to a tetramerizing protein.
Andersson AM, Håkansson KO, Jensen BA, Christensen D, Andersen P, Thomsen AR, Christensen JP.
PLoS One. 2012;7(10):e46395. doi: 10.1371/journal.pone.0046395. Epub 2012 Oct 1.
Pre-existing vector immunity does not prevent replication deficient adenovirus from inducing efficient CD8 T-cell memory and recall responses.
Steffensen MA, Jensen BA, Holst PJ, Bassi MR, Christensen JP, Thomsen AR.
PLoS One. 2012;7(4):e34884. doi: 10.1371/journal.pone.0034884. Epub 2012 Apr 13.

Activated human CD4+ T cells express transporters for both cysteine and cystine.

Levring TB, Hansen AK, Nielsen BL, Kongsbak M, von Essen MR, Woetmann A, Odum N, Bonefeld CM, Geisler C.

Sci Rep. 2012;2:266. doi: 10.1038/srep00266. Epub 2012 Feb 14.

B cells exposed to enterobacterial components suppress development of experimental colitis.

Schmidt EG, Larsen HL, Kristensen NN, Poulsen SS, Claesson MH, Pedersen AE.

Inflamm Bowel Dis. 2012 Feb;18(2):284-93. doi: 10.1002/ibd.21769. Epub 2011 May 25.

Cancer associated aberrant protein O-glycosylation can modify antigen processing and immune response.

Madsen CB, Petersen C, Lavrsen K, Harndahl M, Buus S, Clausen H, Pedersen AE, Wandall HH.

PLoS One. 2012;7(11):e50139. doi: 10.1371/journal.pone.0050139. Epub 2012 Nov 26.

2011
Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient mice.
Holst PJ, Christensen JP, Thomsen AR.
J Immunol. 2011 Apr 1;186(7):3997-4007. doi: 10.4049/jimmunol.1001251. Epub 2011 Feb 28.

Enhanced sensitization and elicitation responses caused by mixtures of common fragrance allergens.

Bonefeld CM, Nielsen MM, Rubin IM, Vennegaard MT, Dabelsteen S, Gimenéz-Arnau E, Lepoittevin JP, Geisler C, Johansen JD.

Contact Dermatitis. 2011 Dec;65(6):336-42. doi: 10.1111/j.1600-0536.2011.01945.x. Epub 2011 Jul 18.

TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections.

Hansen AK, Regner M, Bonefeld CM, Boding L, Kongsbak M, Ødum N, Müllbacher A, Geisler C, von Essen MR.

Eur J Immunol. 2011 Jul;41(7):1948-57. doi: 10.1002/eji.201141413. Epub 2011 May 27.

Enteroantigen-presenting B cells efficiently stimulate CD4(+) T cells in vitro.

Schmidt EG, Kristensen NN, Claesson MH, Pedersen AE.

Inflamm Bowel Dis. 2011 Jan;17(1):308-18. doi: 10.1002/ibd.21429. Epub 2010 Aug 18.

Monocytes mediate shaving of B-cell-bound anti-CD20 antibodies.

Pedersen AE, Jungersen MB, Pedersen CD.

Immunology. 2011 Jun;133(2):239-45. doi: 10.1111/j.1365-2567.2011.03434.x. Epub 2011 Mar 23.

2010

Vitamin D controls T cell antigen receptor signaling and activation of human T cells.

von Essen MR, Kongsbak M, Schjerling P, Olgaard K, Odum N, Geisler C.

Nat Immunol. 2010 Apr;11(4):344-9. doi: 10.1038/ni.1851. Epub 2010 Mar 7.